Scene iii:
At a park near the royal palace, the two felons joined by a third murderer attack Banquo and Fleance. Banquo is killed, but Fleance escapes.

Scene iv:
At the palace, a banquet is being held by Macbeth when one of the murderers arrives at the door and informs the new king of what has occurred. When Macbeth returns to his guests, he sees the ghost of Banquo at the table. Although no one else perceives the ghost, Macbeth is visibly shaken by this vision. Lady Macbeth explains to their guests that her husband is suffering from a periodic illness, that his fit is but momentary. Macbeth appears to recover, but then the Ghost of Banquo appears to him again. The banquet ends abruptly and when the rest leave, Macbeth tells his wife that he will seek out the witches to learn about all the remaining threats against them.

Scene v:
In an "open place," the demon goddess Hectate scolds the three witches for not including her in their plans for Macbeth. She advises them to make-up potent spells to cast on Macbeth when they meet him again.

Scene vi:
In another part of Scotland, the noble Lenox and a second lord talk about the deaths of Duncan and Banquo and relate the news that Duncan's son Malcolm is in England gathering an army to overthrow Macbeth. Along with Macduff and the King of England, Lenox supports the cause of Malcolm to wrest the throne from the murderous Macbeth.